Cyclin K and cyclin D1b are oncogenic in myeloma cells

BACKGROUND: Aberrant expression of cyclin D1 is a common feature in multiple myeloma (MM) and always associated with mantle cell lymphoma (MCL). CCND1 gene is alternatively spliced to produce two cyclin D1 mRNA isoforms which are translated in two proteins: cyclin D1a and cyclin D1b. Both isoforms a...

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Detalles Bibliográficos
Autores principales: Marsaud, Véronique, Tchakarska, Guergana, Andrieux, Geoffroy, Liu, Jian-Miao, Dembele, Doulaye, Jost, Bernard, Wdzieczak-Bakala, Joanna, Renoir, Jack-Michel, Sola, Brigitte
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881116/
https://www.ncbi.nlm.nih.gov/pubmed/20459741
http://dx.doi.org/10.1186/1476-4598-9-103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881116/
https://www.ncbi.nlm.nih.gov/pubmed/20459741
http://dx.doi.org/10.1186/1476-4598-9-103

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