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Cyclin K and cyclin D1b are oncogenic in myeloma cells
BACKGROUND: Aberrant expression of cyclin D1 is a common feature in multiple myeloma (MM) and always associated with mantle cell lymphoma (MCL). CCND1 gene is alternatively spliced to produce two cyclin D1 mRNA isoforms which are translated in two proteins: cyclin D1a and cyclin D1b. Both isoforms a...
Autores principales: | Marsaud, Véronique, Tchakarska, Guergana, Andrieux, Geoffroy, Liu, Jian-Miao, Dembele, Doulaye, Jost, Bernard, Wdzieczak-Bakala, Joanna, Renoir, Jack-Michel, Sola, Brigitte |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881116/ https://www.ncbi.nlm.nih.gov/pubmed/20459741 http://dx.doi.org/10.1186/1476-4598-9-103 |
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