Cargando…

Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells

BACKGROUND: Translational control mediated by non-coding microRNAs (miRNAs) plays a key role in the mechanism of cellular resistance to anti-cancer drug treatment. Dihydrofolate reductase (DHFR) and thymidylate synthase (TYMS, TS) are two of the most important targets for antifolate- and fluoropyrim...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Bo, Wang, Yuan, Titmus, Matthew A, Botchkina, Galina, Formentini, Andrea, Kornmann, Marko, Ju, Jingfang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881118/
https://www.ncbi.nlm.nih.gov/pubmed/20433742
http://dx.doi.org/10.1186/1476-4598-9-96