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Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells
BACKGROUND: Translational control mediated by non-coding microRNAs (miRNAs) plays a key role in the mechanism of cellular resistance to anti-cancer drug treatment. Dihydrofolate reductase (DHFR) and thymidylate synthase (TYMS, TS) are two of the most important targets for antifolate- and fluoropyrim...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881118/ https://www.ncbi.nlm.nih.gov/pubmed/20433742 http://dx.doi.org/10.1186/1476-4598-9-96 |