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Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells

BACKGROUND: Translational control mediated by non-coding microRNAs (miRNAs) plays a key role in the mechanism of cellular resistance to anti-cancer drug treatment. Dihydrofolate reductase (DHFR) and thymidylate synthase (TYMS, TS) are two of the most important targets for antifolate- and fluoropyrim...

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Detalles Bibliográficos
Autores principales:	Song, Bo, Wang, Yuan, Titmus, Matthew A, Botchkina, Galina, Formentini, Andrea, Kornmann, Marko, Ju, Jingfang
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881118/ https://www.ncbi.nlm.nih.gov/pubmed/20433742 http://dx.doi.org/10.1186/1476-4598-9-96

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