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A dynamic Bayesian network for identifying protein-binding footprints from single molecule-based sequencing data
Motivation: A global map of transcription factor binding sites (TFBSs) is critical to understanding gene regulation and genome function. DNaseI digestion of chromatin coupled with massively parallel sequencing (digital genomic footprinting) enables the identification of protein-binding footprints wi...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881360/ https://www.ncbi.nlm.nih.gov/pubmed/20529925 http://dx.doi.org/10.1093/bioinformatics/btq175 |