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A dynamic Bayesian network for identifying protein-binding footprints from single molecule-based sequencing data

Motivation: A global map of transcription factor binding sites (TFBSs) is critical to understanding gene regulation and genome function. DNaseI digestion of chromatin coupled with massively parallel sequencing (digital genomic footprinting) enables the identification of protein-binding footprints wi...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoyu, Hoffman, Michael M., Bilmes, Jeff A., Hesselberth, Jay R., Noble, William S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881360/
https://www.ncbi.nlm.nih.gov/pubmed/20529925
http://dx.doi.org/10.1093/bioinformatics/btq175