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Assessing the functional coherence of gene sets with metrics based on the Gene Ontology graph

Motivation: The results of initial analyses for many high-throughput technologies commonly take the form of gene or protein sets, and one of the ensuing tasks is to evaluate the functional coherence of these sets. The study of gene set function most commonly makes use of controlled vocabulary in the...

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Detalles Bibliográficos
Autores principales: Richards, Adam J., Muller, Brian, Shotwell, Matthew, Cowart, L. Ashley, Rohrer, Bäerbel, Lu, Xinghua
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881388/
https://www.ncbi.nlm.nih.gov/pubmed/20529941
http://dx.doi.org/10.1093/bioinformatics/btq203