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Estimating genome-wide IBD sharing from SNP data via an efficient hidden Markov model of LD with application to gene mapping

Motivation: Association analysis is the method of choice for studying complex multifactorial diseases. The premise of this method is that affected persons contain some common genomic regions with similar SNP alleles and such areas will be found in this analysis. An important disadvantage of GWA stud...

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Detalles Bibliográficos
Autores principales: Bercovici, Sivan, Meek, Christopher, Wexler, Ydo, Geiger, Dan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881389/
https://www.ncbi.nlm.nih.gov/pubmed/20529903
http://dx.doi.org/10.1093/bioinformatics/btq204