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HangOut: generating clean PSI-BLAST profiles for domains with long insertions
Summary: Profile-based similarity search is an essential step in structure-function studies of proteins. However, inclusion of non-homologous sequence segments into a profile causes its corruption and results in false positives. Profile corruption is common in multidomain proteins, and single domain...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881392/ https://www.ncbi.nlm.nih.gov/pubmed/20413635 http://dx.doi.org/10.1093/bioinformatics/btq208 |