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Infection with AV-SUR2A protects H9C2 cells against metabolic stress: A mechanism of SUR2A-mediated cytoprotection independent from the K(ATP) channel activity

Transgenic mice overexpressing SUR2A, a subunit of ATP-sensitive K(+) (K(ATP)) channels, acquire resistance to myocardial ischaemia. However, the mechanism of SUR2A-mediated cytoprotection is yet to be fully understood. Adenoviral SUR2A construct (AV-SUR2A) increased SUR2A expression, number of K(AT...

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Detalles Bibliográficos
Autores principales: Du, Qingyou, Jovanović, Sofija, Sukhodub, Andriy, Jovanović, Aleksandar
Formato: Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881534/
https://www.ncbi.nlm.nih.gov/pubmed/20123112
http://dx.doi.org/10.1016/j.bbamcr.2010.01.018