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Damaged DNA-binding Protein 1 (DDB1) Interacts with Cdh1 and Modulates the Function of APC/C(Cdh1)

APC/C(Cdh1) plays a key role in mitotic exit and has essential targets in the G(1) phase; however, these mechanisms are poorly understood. In this report, we provide evidence that damaged DNA-binding protein 1 (DDB1) is capable of binding the WD40 domains of Cdh1, but not of Cdc20, through its BPA a...

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Detalles Bibliográficos
Autores principales: Lv, Xiao-Bin, Xie, Fangyun, Hu, Kaishun, Wu, Yuanzhong, Cao, Lin-Lin, Han, Xia, Sang, Yi, Zeng, Yi-Xin, Kang, Tiebang
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881748/
https://www.ncbi.nlm.nih.gov/pubmed/20395298
http://dx.doi.org/10.1074/jbc.M109.094144