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Effective in vivo and ex vivo gene transfer to intestinal mucosa by VSV-G-pseudotyped lentiviral vectors

BACKGROUND: Gene transfer to the gastrointestinal (GI) mucosa is a therapeutic strategy which could prove particularly advantageous for treatment of various hereditary and acquired intestinal disorders, including inflammatory bowel disease (IBD), GI infections, and cancer. METHODS: We evaluated vesi...

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Detalles Bibliográficos
Autores principales: Matsumoto, Hiroshi, Kimura, Takahiro, Haga, Kazunori, Kasahara, Noriyuki, Anton, Peter, McGowan, Ian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881878/
https://www.ncbi.nlm.nih.gov/pubmed/20459837
http://dx.doi.org/10.1186/1471-230X-10-44