Subchronic exposure to phytoestrogens alone and in combination with diethylstilbestrol - pituitary tumor induction in Fischer 344 rats

BACKGROUND: Subchronic administration of the potent pharmaceutical estrogen diethylstilbestrol (DES) to female Fischer 344 (F344) rats induces growth of large, hemorrhagic pituitaries that progress to tumors. Phytoestrogens (dietary plant estrogens) are hypothesized to be potential tumor inhibitors...

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Detalles Bibliográficos
Autores principales: Jeng, Yow-Jiun, Kochukov, Mikhail, Nauduri, Dhananjaya, Kaphalia, Bhupendra S, Watson, Cheryl S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881934/
https://www.ncbi.nlm.nih.gov/pubmed/20459739
http://dx.doi.org/10.1186/1743-7075-7-40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881934/
https://www.ncbi.nlm.nih.gov/pubmed/20459739
http://dx.doi.org/10.1186/1743-7075-7-40

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