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Plasmodium chabaudi chabaudi malaria parasites can develop stable resistance to atovaquone with a mutation in the cytochrome b gene

BACKGROUND: Plasmodium falciparum, has developed resistance to many of the drugs in use. The recommended treatment policy is now to use drug combinations. The atovaquone-proguanil (AP) drug combination, is one of the treatment and prophylaxis options. Atovaquone (ATQ) exerts its action by inhibiting...

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Detalles Bibliográficos
Autores principales: Afonso, Ana, Neto, Zoraima, Castro, Helena, Lopes, Dinora, Alves, Ana C, Tomás, Ana M, Rosário, Virgílio D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881937/
https://www.ncbi.nlm.nih.gov/pubmed/20492669
http://dx.doi.org/10.1186/1475-2875-9-135