An Antimicrobial Peptide Regulates Tumor-Associated Macrophage Trafficking via the Chemokine Receptor CCR2, a Model for Tumorigenesis

BACKGROUND: Tumor-associated macrophages (TAMs) constitute a significant part of infiltrating inflammatory cells that are frequently correlated with progression and poor prognosis of a variety of cancers. Tumor cell-produced human β-defensin-3 (hBD-3) has been associated with TAM trafficking in oral...

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Detalles Bibliográficos
Autores principales: Jin, Ge, Kawsar, Hameem I., Hirsch, Stanley A., Zeng, Chun, Jia, Xun, Feng, Zhimin, Ghosh, Santosh K., Zheng, Qing Yin, Zhou, Aimin, McIntyre, Thomas M., Weinberg, Aaron
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882331/
https://www.ncbi.nlm.nih.gov/pubmed/20544025
http://dx.doi.org/10.1371/journal.pone.0010993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882331/
https://www.ncbi.nlm.nih.gov/pubmed/20544025
http://dx.doi.org/10.1371/journal.pone.0010993

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