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Characterization of bortezomib-adapted I-45 mesothelioma cells

BACKGROUND: Bortezomib, a proteasome-specific inhibitor, has emerged as a promising cancer therapeutic agent. However, development of resistance to bortezomib may pose a challenge to effective anticancer therapy. Therefore, characterization of cellular mechanisms involved in bortezomib resistance an...

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Detalles Bibliográficos
Autores principales: Zhang, Lidong, Littlejohn, James E, Cui, Yu, Cao, Xiaobo, Peddaboina, Chander, Smythe, W Roy
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882347/
https://www.ncbi.nlm.nih.gov/pubmed/20482802
http://dx.doi.org/10.1186/1476-4598-9-110