Cell Cycle and Anti-Estrogen Effects Synergize to Regulate Cell Proliferation and ER Target Gene Expression

Antiestrogens are designed to antagonize hormone induced proliferation and ERα target gene expression in mammary tumor cells. Commonly used drugs such as OH-Tamoxifen and ICI 182780 (Fulvestrant) block cell cycle progression in G0/G1. Inversely, the effect of cell cycle stage on ER regulated gene ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Dalvai, Mathieu, Bystricky, Kerstin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882356/
https://www.ncbi.nlm.nih.gov/pubmed/20543978
http://dx.doi.org/10.1371/journal.pone.0011011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882356/
https://www.ncbi.nlm.nih.gov/pubmed/20543978
http://dx.doi.org/10.1371/journal.pone.0011011

Ejemplares similares