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Proinflammatory Phenotype and Increased Caveolin-1 in Alveolar Macrophages with Silenced CFTR mRNA

The inflammatory milieu in the respiratory tract in cystic fibrosis (CF) has been linked to the defective expression of the cystic transmembrane regulator (CFTR) in epithelial cells. Alveolar macrophages (AM), important contibutors to inflammatory responses in the lung, also express CFTR. The presen...

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Detalles Bibliográficos
Autores principales: Xu, Yaqin, Krause, Anja, Hamai, Hiroko, Harvey, Ben-Gary, Worgall, Tilla S., Worgall, Stefan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882373/
https://www.ncbi.nlm.nih.gov/pubmed/20543983
http://dx.doi.org/10.1371/journal.pone.0011004