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Protein binding hot spots and the residue-residue pairing preference: a water exclusion perspective

BACKGROUND: A protein binding hot spot is a small cluster of residues tightly packed at the center of the interface between two interacting proteins. Though a hot spot constitutes a small fraction of the interface, it is vital to the stability of protein complexes. Recently, there are a series of hy...

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Detalles Bibliográficos
Autores principales: Liu, Qian, Li, Jinyan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882391/
https://www.ncbi.nlm.nih.gov/pubmed/20462403
http://dx.doi.org/10.1186/1471-2105-11-244