Role of endosomal membrane lipids and NPC2 in cholesterol transfer and membrane fusion

We examined the effect of Niemann-Pick disease type 2 (NPC2) protein and some late endosomal lipids [sphingomyelin, ceramide and bis(monoacylglycero)phosphate (BMP)] on cholesterol transfer and membrane fusion. Of all lipid-binding proteins tested, only NPC2 transferred cholesterol at a substantial...

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Detalles Bibliográficos
Autores principales: Abdul-Hammed, Misbaudeen, Breiden, Bernadette, Adebayo, Matthew A., Babalola, Jonathan O., Schwarzmann, Günter, Sandhoff, Konrad
Formato: Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882726/
https://www.ncbi.nlm.nih.gov/pubmed/20179319
http://dx.doi.org/10.1194/jlr.M003822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882726/
https://www.ncbi.nlm.nih.gov/pubmed/20179319
http://dx.doi.org/10.1194/jlr.M003822

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