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Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment

Hematopoietic stem cells (HSCs) have been extensively characterized based on functional definitions determined by experimental transplantation into lethally irradiated mice. In mice, HSCs are heterogeneous with regard to self-renewal potential, in vitro colony-forming activity, and in vivo behavior....

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Detalles Bibliográficos
Autores principales: Morita, Yohei, Ema, Hideo, Nakauchi, Hiromitsu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882827/
https://www.ncbi.nlm.nih.gov/pubmed/20421392
http://dx.doi.org/10.1084/jem.20091318