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Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment
Hematopoietic stem cells (HSCs) have been extensively characterized based on functional definitions determined by experimental transplantation into lethally irradiated mice. In mice, HSCs are heterogeneous with regard to self-renewal potential, in vitro colony-forming activity, and in vivo behavior....
Autores principales: | Morita, Yohei, Ema, Hideo, Nakauchi, Hiromitsu |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882827/ https://www.ncbi.nlm.nih.gov/pubmed/20421392 http://dx.doi.org/10.1084/jem.20091318 |
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