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IL-10 administration reduces PGE-2 levels and promotes CR3-mediated clearance of Escherichia coli K1 by phagocytes in meningitis

Ineffectiveness of antibiotics in treating neonatal Escherichia coli K1 meningitis and the emergence of antibiotic-resistant strains evidently warrants new prevention strategies. We observed that administration of interleukin (IL)-10 during high-grade bacteremia clears antibiotic-sensitive and -resi...

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Detalles Bibliográficos
Autores principales: Mittal, Rahul, Gonzalez-Gomez, Ignacio, Panigrahy, Ashok, Goth, Kerstin, Bonnet, Richard, Prasadarao, Nemani V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882833/
https://www.ncbi.nlm.nih.gov/pubmed/20498022
http://dx.doi.org/10.1084/jem.20092265