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One naive T cell, multiple fates in CD8(+) T cell differentiation

The mechanism by which the immune system produces effector and memory T cells is largely unclear. To allow a large-scale assessment of the development of single naive T cells into different subsets, we have developed a technology that introduces unique genetic tags (barcodes) into naive T cells. By...

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Detalles Bibliográficos
Autores principales: Gerlach, Carmen, van Heijst, Jeroen W.J., Swart, Erwin, Sie, Daoud, Armstrong, Nicola, Kerkhoven, Ron M., Zehn, Dietmar, Bevan, Michael J., Schepers, Koen, Schumacher, Ton N.M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882844/
https://www.ncbi.nlm.nih.gov/pubmed/20479114
http://dx.doi.org/10.1084/jem.20091175