Targeting tissue factor on tumour cells and angiogenic vascular endothelial cells by factor VII-targeted verteporfin photodynamic therapy for breast cancer in vitro and in vivo in mice

BACKGROUND: The objective of this study was to develop a ligand-targeted photodynamic therapy (tPDT) by conjugating factor VII (fVII) protein with photosensitiser verteporfin in order to overcome the poor selectivity and enhance the effect of non-targeted PDT (ntPDT) for cancer. fVII is a natural li...

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Detalles Bibliográficos
Autores principales: Hu, Zhiwei, Rao, Benqiang, Chen, Shimin, Duanmu, Jinzhong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882923/
https://www.ncbi.nlm.nih.gov/pubmed/20504328
http://dx.doi.org/10.1186/1471-2407-10-235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882923/
https://www.ncbi.nlm.nih.gov/pubmed/20504328
http://dx.doi.org/10.1186/1471-2407-10-235

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