A comprehensive survey of human polymorphisms at conserved splice dinucleotides and its evolutionary relationship with alternative splicing

BACKGROUND: Alternative splicing (AS) is a key molecular process that endows biological functions with diversity and complexity. Generally, functional redundancy leads to the generation of new functions through relaxation of selective pressure in evolution, as exemplified by duplicated genes. It is...

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Detalles Bibliográficos
Autores principales: Shimada, Makoto K, Hayakawa, Yosuke, Takeda, Jun-ichi, Gojobori, Takashi, Imanishi, Tadashi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882926/
https://www.ncbi.nlm.nih.gov/pubmed/20433709
http://dx.doi.org/10.1186/1471-2148-10-122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882926/
https://www.ncbi.nlm.nih.gov/pubmed/20433709
http://dx.doi.org/10.1186/1471-2148-10-122

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