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Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer

BACKGROUND: LIM and SH3 protein 1 (LASP-1) is a nucleo-cytoplasmatic signalling protein involved in cell proliferation and migration and is upregulated in breast cancer in vitro studies have shown that LASP-1 might be regulated by prostate-derived ETS factor (PDEF), p53 and/or LASP1 gene amplificati...

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Detalles Bibliográficos
Autores principales: Frietsch, J J, Grunewald, T G P, Jasper, S, Kammerer, U, Herterich, S, Kapp, M, Honig, A, Butt, E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883150/
https://www.ncbi.nlm.nih.gov/pubmed/20461080
http://dx.doi.org/10.1038/sj.bjc.6605685