Image cytometry accurately detects DNA ploidy abnormalities and predicts late relapse to high-grade dysplasia and adenocarcinoma in Barrett's oesophagus following photodynamic therapy

BACKGROUND AND AIMS: DNA ploidy abnormalities (aneuploidy/tetraploidy) measured by flow cytometry (FC) are strong predictors of future cancer development in untreated Barrett's oesophagus, independent of histology grade. Image cytometric DNA analysis (ICDA) is an optical technique allowing visu...

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Detalles Bibliográficos
Autores principales: Dunn, J M, Mackenzie, G D, Oukrif, D, Mosse, C A, Banks, M R, Thorpe, S, Sasieni, P, Bown, S G, Novelli, M R, Rabinovitch, P S, Lovat, L B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883155/
https://www.ncbi.nlm.nih.gov/pubmed/20461081
http://dx.doi.org/10.1038/sj.bjc.6605688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883155/
https://www.ncbi.nlm.nih.gov/pubmed/20461081
http://dx.doi.org/10.1038/sj.bjc.6605688

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