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STAT3 inhibitor WP1066 as a novel therapeutic agent for renal cell carcinoma

BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) regulates the expression of genes that mediate cell survival, proliferation, and angiogenesis and is aberrantly activated in various types of malignancies, including renal cell carcinoma (RCC). We examined whether it could be a n...

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Detalles Bibliográficos
Autores principales: Horiguchi, A, Asano, T, Kuroda, K, Sato, A, Asakuma, J, Ito, K, Hayakawa, M, Sumitomo, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883159/
https://www.ncbi.nlm.nih.gov/pubmed/20461084
http://dx.doi.org/10.1038/sj.bjc.6605691