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A retroviral mutagenesis screen identifies Cd74 as a common insertion site in murine B-lymphomas and reveals the existence of a novel IFNγ-inducible Cd74 isoform

BACKGROUND: Insertional mutagenesis screens in the mouse are an acknowledged approach to identify genes involved in the pathogenesis of cancer. The potential of these screens to identify genes causally involved in tumorigenesis is not only limited to the murine host, but many of these genes have als...

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Detalles Bibliográficos
Autores principales: Pyrz, Magdalena, Wang, Bruce, Wabl, Matthias, Pedersen, Finn Skou
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883540/
https://www.ncbi.nlm.nih.gov/pubmed/20416035
http://dx.doi.org/10.1186/1476-4598-9-86