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A retroviral mutagenesis screen identifies Cd74 as a common insertion site in murine B-lymphomas and reveals the existence of a novel IFNγ-inducible Cd74 isoform
BACKGROUND: Insertional mutagenesis screens in the mouse are an acknowledged approach to identify genes involved in the pathogenesis of cancer. The potential of these screens to identify genes causally involved in tumorigenesis is not only limited to the murine host, but many of these genes have als...
Autores principales: | Pyrz, Magdalena, Wang, Bruce, Wabl, Matthias, Pedersen, Finn Skou |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883540/ https://www.ncbi.nlm.nih.gov/pubmed/20416035 http://dx.doi.org/10.1186/1476-4598-9-86 |
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