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Detection of Botulinum Neurotoxin Serotype B at Sub Mouse LD(50) Levels by a Sandwich Immunoassay and Its Application to Toxin Detection in Milk
BACKGROUND: Botulinum neurotoxin (BoNT), the causative agent of botulism, a serious neuroparylatic disease, is produced by the anaerobic bacterium Clostridium botulinum and consists of a family of seven serotypes (A-H). We previously reported production of high-affinity monoclonal antibodies to BoNT...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883556/ https://www.ncbi.nlm.nih.gov/pubmed/20548779 http://dx.doi.org/10.1371/journal.pone.0011047 |