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Contrasting Transcriptional Responses of a Virulent and an Attenuated Strain of Mycobacterium tuberculosis Infecting Macrophages

BACKGROUND: H37Rv and H37Ra are well-described laboratory strains of Mycobacterium tuberculosis derived from the same parental strain, H37, that show dramatically different pathogenic phenotypes. METHODOLOGY/PRINCIPAL FINDINGS: In this study, the transcriptomes of the two strains during axenic growt...

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Detalles Bibliográficos
Autores principales: Li, Alice H., Waddell, Simon J., Hinds, Jason, Malloff, Chad A., Bains, Manjeet, Hancock, Robert E., Lam, Wan L., Butcher, Philip D., Stokes, Richard W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883559/
https://www.ncbi.nlm.nih.gov/pubmed/20548782
http://dx.doi.org/10.1371/journal.pone.0011066