Application of Equilibrium Models of Solution Hybridization to Microarray Design and Analysis

BACKGROUND: The probe percent bound value, calculated using multi-state equilibrium models of solution hybridization, is shown to be useful in understanding the hybridization behavior of microarray probes having 50 nucleotides, with and without mismatches. These longer oligonucleotides are in widesp...

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Detalles Bibliográficos
Autores principales: Gharaibeh, Raad Z., Newton, Joshua M., Weller, Jennifer W., Gibas, Cynthia J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883574/
https://www.ncbi.nlm.nih.gov/pubmed/20548788
http://dx.doi.org/10.1371/journal.pone.0011048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883574/
https://www.ncbi.nlm.nih.gov/pubmed/20548788
http://dx.doi.org/10.1371/journal.pone.0011048

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