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Application of Equilibrium Models of Solution Hybridization to Microarray Design and Analysis
BACKGROUND: The probe percent bound value, calculated using multi-state equilibrium models of solution hybridization, is shown to be useful in understanding the hybridization behavior of microarray probes having 50 nucleotides, with and without mismatches. These longer oligonucleotides are in widesp...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883574/ https://www.ncbi.nlm.nih.gov/pubmed/20548788 http://dx.doi.org/10.1371/journal.pone.0011048 |