Cargando…

Employing Information Theoretic Measures and Mutagenesis to Identify Residues Critical for Drug-Proton Antiport Function in Mdr1p of Candida albicans

By employing information theoretic measures, this study presents a structure and functional analysis of a multidrug-proton antiporter Mdr1p of Candida albicans. Since CaMdr1p belongs to drug-proton antiporter (DHA1) family of Major Facilitator Superfamily (MFS) of transporters, we contrasted DHA1 (a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kapoor, Khyati, Rehan, Mohd, Lynn, Andrew M., Prasad, Rajendra
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883579/
https://www.ncbi.nlm.nih.gov/pubmed/20548793
http://dx.doi.org/10.1371/journal.pone.0011041