Cargando…
Employing Information Theoretic Measures and Mutagenesis to Identify Residues Critical for Drug-Proton Antiport Function in Mdr1p of Candida albicans
By employing information theoretic measures, this study presents a structure and functional analysis of a multidrug-proton antiporter Mdr1p of Candida albicans. Since CaMdr1p belongs to drug-proton antiporter (DHA1) family of Major Facilitator Superfamily (MFS) of transporters, we contrasted DHA1 (a...
Autores principales: | Kapoor, Khyati, Rehan, Mohd, Lynn, Andrew M., Prasad, Rajendra |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883579/ https://www.ncbi.nlm.nih.gov/pubmed/20548793 http://dx.doi.org/10.1371/journal.pone.0011041 |
Ejemplares similares
-
Rational Mutational Analysis of a Multidrug MFS Transporter CaMdr1p of Candida albicans by Employing a Membrane Environment Based Computational Approach
por: Kapoor, Khyati, et al.
Publicado: (2009) -
Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of Candida albicans
por: Banerjee, Atanu, et al.
Publicado: (2021) -
Novel Regulatory Mechanisms of Pathogenicity and Virulence to Combat MDR in Candida albicans
por: Hameed, Saif, et al.
Publicado: (2013) -
Functionally Relevant Residues of Cdr1p: A Multidrug ABC Transporter of Human Pathogenic Candida albicans
por: Prasad, Rajendra, et al.
Publicado: (2011) -
Maize Transposable Elements Ac/Ds as Insertion Mutagenesis Tools in Candida albicans
por: Mielich, Kevin, et al.
Publicado: (2018)