Two Novel Point Mutations in Clinical Staphylococcus aureus Reduce Linezolid Susceptibility and Switch on the Stringent Response to Promote Persistent Infection

Staphylococcus aureus frequently invades the human bloodstream, leading to life threatening bacteremia and often secondary foci of infection. Failure of antibiotic therapy to eradicate infection is frequently described; in some cases associated with altered S. aureus antimicrobial resistance or the...

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Detalles Bibliográficos
Autores principales: Gao, Wei, Chua, Kyra, Davies, John K., Newton, Hayley J., Seemann, Torsten, Harrison, Paul F., Holmes, Natasha E., Rhee, Hyun-Woo, Hong, Jong-In, Hartland, Elizabeth L., Stinear, Timothy P., Howden, Benjamin P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883592/
https://www.ncbi.nlm.nih.gov/pubmed/20548948
http://dx.doi.org/10.1371/journal.ppat.1000944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883592/
https://www.ncbi.nlm.nih.gov/pubmed/20548948
http://dx.doi.org/10.1371/journal.ppat.1000944

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