Cargando…

Cushing's Syndrome and Fetal Features Resurgence in Adrenal Cortex–Specific Prkar1a Knockout Mice

Carney complex (CNC) is an inherited neoplasia syndrome with endocrine overactivity. Its most frequent endocrine manifestation is primary pigmented nodular adrenocortical disease (PPNAD), a bilateral adrenocortical hyperplasia causing pituitary-independent Cushing's syndrome. Inactivating mutat...

Descripción completa

Detalles Bibliográficos
Autores principales: Sahut-Barnola, Isabelle, de Joussineau, Cyrille, Val, Pierre, Lambert-Langlais, Sarah, Damon, Christelle, Lefrançois-Martinez, Anne-Marie, Pointud, Jean-Christophe, Marceau, Geoffroy, Sapin, Vincent, Tissier, Frédérique, Ragazzon, Bruno, Bertherat, Jérôme, Kirschner, Lawrence S., Stratakis, Constantine A., Martinez, Antoine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883593/
https://www.ncbi.nlm.nih.gov/pubmed/20548949
http://dx.doi.org/10.1371/journal.pgen.1000980