Epigenetic Repression of p16(INK4A) by Latent Epstein-Barr Virus Requires the Interaction of EBNA3A and EBNA3C with CtBP

As an inhibitor of cyclin-dependent kinases, p16(INK4A) is an important tumour suppressor and inducer of cellular senescence that is often inactivated during the development of cancer by promoter DNA methylation. Using newly established lymphoblastoid cell lines (LCLs) expressing a conditional EBNA3...

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Detalles Bibliográficos
Autores principales: Skalska, Lenka, White, Robert E., Franz, Melanie, Ruhmann, Michaela, Allday, Martin J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883600/
https://www.ncbi.nlm.nih.gov/pubmed/20548956
http://dx.doi.org/10.1371/journal.ppat.1000951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883600/
https://www.ncbi.nlm.nih.gov/pubmed/20548956
http://dx.doi.org/10.1371/journal.ppat.1000951

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