Feline Leukemia Virus Integrase And Capsid Packaging Functions Do Not Change The Insertion Profile Of Standard Moloney Retroviral Vectors

Adverse events linked to perturbations of cellular genes by vector insertion reported in gene therapy trials and animal models have prompted attempts to better understand the mechanisms directing viral vector integration. The integration profiles of vectors based on MLV, ASLV, SIV, and HIV have all...

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Detalles Bibliográficos
Autores principales: Métais, Jean-Yves, Topp, Shana, Doty, Raymond T., Borate, Bhavesh, Nguyen, Anh-Dao, Wolfsberg, Tyra G., Abkowitz, Janis L., Dunbar, Cynthia E.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883645/
https://www.ncbi.nlm.nih.gov/pubmed/20237508
http://dx.doi.org/10.1038/gt.2010.24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883645/
https://www.ncbi.nlm.nih.gov/pubmed/20237508
http://dx.doi.org/10.1038/gt.2010.24

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