Casein Kinase 1 Functions as both Penultimate and Ultimate Kinase in Regulating Cdc25A Destruction

The Cdc25A protein phosphatase drives cell cycle transitions by activating cyclin-dependent protein kinases. Failure to regulate Cdc25A leads to deregulated cell cycle progression, bypass of cell cycle checkpoints and genome instability. Ubiquitin-mediated proteolysis plays an important role in bala...

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Detalles Bibliográficos
Autores principales: Honaker, Yuchi, Piwnica-Worms, Helen
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883652/
https://www.ncbi.nlm.nih.gov/pubmed/20348946
http://dx.doi.org/10.1038/onc.2010.96

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883652/
https://www.ncbi.nlm.nih.gov/pubmed/20348946
http://dx.doi.org/10.1038/onc.2010.96

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