Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells

BACKGROUND: Pregnane X receptor (PXR) is a nuclear receptor that regulates the metabolism and disposition of various xenobiotics and endobioitics. We investigated a novel PXR function in regulating colon tumourigenesis in this study. METHODS: Histochemistry, transfection, cell proliferation assay, a...

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Detalles Bibliográficos
Autores principales: Ouyang, N, Ke, S, Eagleton, N, Xie, Y, Chen, G, Laffins, B, Yao, H, Zhou, B, Tian, Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883694/
https://www.ncbi.nlm.nih.gov/pubmed/20531417
http://dx.doi.org/10.1038/sj.bjc.6605677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883694/
https://www.ncbi.nlm.nih.gov/pubmed/20531417
http://dx.doi.org/10.1038/sj.bjc.6605677

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