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Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved

Mycobacterium tuberculosis is an obligate human pathogen capable of persisting in individual hosts for decades. To determine whether antigenic variation and immune escape contribute to the success of M. tuberculosis, we determined and analyzed 22 genome sequences representative of the global diversi...

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Detalles Bibliográficos
Autores principales: Comas, Iñaki, Chakravartti, Jaidip, Small, Peter M., Galagan, James, Niemann, Stefan, Kremer, Kristin, Ernst, Joel D., Gagneux, Sebastien
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883744/
https://www.ncbi.nlm.nih.gov/pubmed/20495566
http://dx.doi.org/10.1038/ng.590