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Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved
Mycobacterium tuberculosis is an obligate human pathogen capable of persisting in individual hosts for decades. To determine whether antigenic variation and immune escape contribute to the success of M. tuberculosis, we determined and analyzed 22 genome sequences representative of the global diversi...
Autores principales: | Comas, Iñaki, Chakravartti, Jaidip, Small, Peter M., Galagan, James, Niemann, Stefan, Kremer, Kristin, Ernst, Joel D., Gagneux, Sebastien |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883744/ https://www.ncbi.nlm.nih.gov/pubmed/20495566 http://dx.doi.org/10.1038/ng.590 |
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