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Rationalizing the development of live attenuated virus vaccines

Since the first demonstration of the protective effects of vaccinia inoculation, vaccination has been one of the medicine’s greatest successes. The design of vaccines against viral disease has evolved considerably over the last 50 years. Classically attenuated viruses, those created by passaging a v...

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Detalles Bibliográficos
Autores principales: Lauring, Adam S., Jones, Jeremy O., Andino, Raul
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883798/
https://www.ncbi.nlm.nih.gov/pubmed/20531338
http://dx.doi.org/10.1038/nbt.1635