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Human K(ATP) channelopathies: diseases of metabolic homeostasis

Assembly of an inward rectifier K(+) channel pore (Kir6.1/Kir6.2) and an adenosine triphosphate (ATP)-binding regulatory subunit (SUR1/SUR2A/SUR2B) forms ATP-sensitive K(+) (K(ATP)) channel heteromultimers, widely distributed in metabolically active tissues throughout the body. K(ATP) channels are m...

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Detalles Bibliográficos
Autores principales: Olson, Timothy M., Terzic, Andre
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883927/
https://www.ncbi.nlm.nih.gov/pubmed/20033705
http://dx.doi.org/10.1007/s00424-009-0771-y