The Molecular Chaperone α-Crystallin as an Excipient in an Insulin Formulation

PURPOSE: To investigate insulin fibrillation under accelerated stress conditions in the presence of a novel excipient, the molecular chaperone α-crystallin, in comparison with common excipients. METHODS: To induce fibrillation, recombinant human insulin (0.58 mg ml(−1)) formulations without excipien...

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Detalles Bibliográficos
Autores principales: Rasmussen, Tue, Tantipolphan, Ruedeeporn, van de Weert, Marco, Jiskoot, Wim
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883933/
https://www.ncbi.nlm.nih.gov/pubmed/20333453
http://dx.doi.org/10.1007/s11095-010-0116-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883933/
https://www.ncbi.nlm.nih.gov/pubmed/20333453
http://dx.doi.org/10.1007/s11095-010-0116-8

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