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BiP Availability Distinguishes States of Homeostasis and Stress in the Endoplasmic Reticulum of Living Cells

Accumulation of misfolded secretory proteins causes cellular stress and induces the endoplasmic reticulum (ER) stress pathway, the unfolded protein response (UPR). Although the UPR has been extensively studied, little is known about the molecular changes that distinguish the homeostatic and stressed...

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Detalles Bibliográficos
Autores principales: Lai, Chun Wei, Aronson, Deborah E., Snapp, Erik Lee
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883936/
https://www.ncbi.nlm.nih.gov/pubmed/20410136
http://dx.doi.org/10.1091/mbc.E09-12-1066