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BiP Availability Distinguishes States of Homeostasis and Stress in the Endoplasmic Reticulum of Living Cells
Accumulation of misfolded secretory proteins causes cellular stress and induces the endoplasmic reticulum (ER) stress pathway, the unfolded protein response (UPR). Although the UPR has been extensively studied, little is known about the molecular changes that distinguish the homeostatic and stressed...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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The American Society for Cell Biology
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883936/ https://www.ncbi.nlm.nih.gov/pubmed/20410136 http://dx.doi.org/10.1091/mbc.E09-12-1066 |