Insulin-regulated Aminopeptidase Is a Key Regulator of GLUT4 Trafficking by Controlling the Sorting of GLUT4 from Endosomes to Specialized Insulin-regulated Vesicles

Insulin stimulates glucose uptake by regulating translocation of the GLUT4 glucose transporter from intracellular compartments to the plasma membrane. In the absence of insulin GLUT4 is actively sequestered away from the general endosomes into GLUT4-specialized compartments, thereby controlling the...

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Detalles Bibliográficos
Autores principales: Jordens, Ingrid, Molle, Dorothee, Xiong, Wenyong, Keller, Susanna R., McGraw, Timothy E.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883947/
https://www.ncbi.nlm.nih.gov/pubmed/20410133
http://dx.doi.org/10.1091/mbc.E10-02-0158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883947/
https://www.ncbi.nlm.nih.gov/pubmed/20410133
http://dx.doi.org/10.1091/mbc.E10-02-0158

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