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Neuralized Promotes Basal to Apical Transcytosis of Delta in Epithelial Cells

Notch receptors mediate short-range signaling controlling many developmental decisions in metazoans. Activation of Notch requires the ubiquitin-dependent endocytosis of its ligand Delta. How ligand endocytosis in signal-sending cells regulates receptor activation in juxtaposed signal-receiving cells...

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Detalles Bibliográficos
Autores principales: Benhra, Najate, Vignaux, Françoise, Dussert, Aurore, Schweisguth, François, Le Borgne, Roland
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883951/
https://www.ncbi.nlm.nih.gov/pubmed/20410139
http://dx.doi.org/10.1091/mbc.E09-11-0926